In this project, the candidate will work on a multidisciplinary project in collaboration with international collaborators. The goal is to develop a new sensor technology for the detection of PFAS molecules in environmental samples.
The PhD project is focused on the development of sensory platforms based on Molecularly Imprinted Polymers (MIPs) for the detection of polyfluoroalkyl substances (PFAS). MIPs are the synthetic equivalent of antibodies, consisting of a highly crosslinked polymeric network with molecule-specific active/binding sites distributed throughout that are generated during the synthesis process. The manner in which this is achieved varies, though all routes lean on polymer formation around a desired molecular template accompanied by its later extraction. This process can be likened to molding dough around a key to capture its likeness, but on a molecular level. In the past, the SE department has successfully developed MIPs for glucose, pyocyanin, drugs of abuse and even some PFAS. This project therefore seeks to build on what we have previously attained, with the selected PhD student furthering our research in the field of PFAS detection.
The driving force behind this project is the increasing need for an easier means of PFAS recognition, with this class of compounds being known as “forever chemicals” as they are extremely persistent and may even lead to health problems such as liver damage, thyroid disease, cancer, obesity and fertility issues. It is for this reason that the European Union is tightening restrictions regarding PFAS, and land development is a process that is increasingly scrutinized for the potential presence of these contaminants. It is therefore our aim to synthesize more sophisticated, reliable and sensitive MIPs for PFAS detection, with environmental analysis being the ultimate goal. The project seeks to develop sensing platforms that provide the rapid confirmation of PFAS contaminants, minimizing exposure and helping to identify environmental areas of concern.
Research within the Sensor Engineering research group at the Faculty of Science and Engineering of Maastricht University is focused on developing innovative sensor technologies for implementation in diverse fields ranging from medical diagnostics to food safety assessment. For this position, we are looking for a motivated PhD student with a master degree and a solid background in bio-, organic, polymer or analytical chemistry. The candidate will work in a multicultural, interdisciplinary team consisting of engineers, chemists and biomedical scientists. The research group has developed extensive expertise in combining sensor technology with chemistry and biomedical engineering to acquire knowledge and streamline applications for use in real life settings.
As a PhD student your tasks include:
- Lead your own research project independently (although supervision by expert researchers will be provided)
- Study literature
- Develop research plan
- Experimentation and data processing
- Biofunctionalization of interfaces
- Optical and electrochemical transducers
- Scientific Dissemination: writing articles and participating in international conferences
- Contribute to the teaching activities of the department, mostly as a tutor or lab supervisor