Preference measurement for low-risk ductal carcinoma in situ (DCIS) management

Preference measurement for low-risk ductal carcinoma in situ (DCIS) management

Published Deadline Location
18 Dec 1 Feb Rotterdam
Voorkomen van onnodige behandeling voor laagrisico ductal carcinoma in situ (DCIS) is ons doel. Hoe beïnvloedt risicovoorspelling de behandelkeuzes van vrouwen?

Job description

Ductal carcinoma in situ (DCIS) is considered a preliminary stage of breast cancer, but most DCIS cases do not progress to invasive cancer. Currently, because we cannot distinguish harmless cases from those that may advance, nearly all women with DCIS undergo aggressive treatments like surgery (even mastectomy), with or without radiotherapy. Our goal is to avoid unnecessary treatments for low-risk DCIS, preserving survival and quality of life.

The "Direct-DCIS" project, launched under the Dutch National Science Agenda (NWA) in 2024, aims to address this. Through advanced AI and large patient datasets, this project will develop a model to predict the likelihood of DCIS progressing to invasive cancer. This research involves a diverse team—epidemiologists, radiologists, pathologists, AI experts, health economists, and patients—working together to make precise, patient-centred care possible.

The Health Technology Assessment (HTA) group at Erasmus School of Health Policy & Management (ESHPM), in partnership with the HTA group at the Netherlands Cancer Institute (NKI), leads the Work Package on ‘Patient Preferences and Health Technology Assessment’, to support evidence-based treatment decisions for DCIS.

Job description
This vacancy is for a PhD candidate who will principally focus on obtaining insights into preferences for low-risk DCIS management. The PhD candidate’s job description will be to determine (1) what impact DCIS-risk forecasting has on women’s preferences for DCIS management; (2) what preferences DCIS women and health stakeholders have for different DCIS management characteristics and which trade-offs they make; (3) what uptake of DCIS active surveillance scenarios can be expected for (different subgroups of) low-risk DCIS women; (4) what factors influence (non-)adherence most in DCIS active surveillance treatment; and (5) how to integrate and weight DCIS women’s preferences into an early HTA best. Hereto, the candidate will develop and conduct a mixed method approach, including literature study, interviews and focus groups with DCIS women and health professionals, discrete choice experiments, and natural field experiments. The PhD candidate will work closely with another PhD—who is constructing a dynamic cost-effectiveness model based on national retrospective and prospective data—on these tasks. Besides research responsibilities, the PhD candidate will also participate in our teaching programs (up to 0.15fte) and be given opportunity to learn and develop knowledge and skills i.a. by taking graduate courses.

Specifications

Erasmus University Rotterdam (EUR)

Requirements

The successful applicant for this position is expected to have a recent or almost completed relevant MSc degree in health economics, behavioural economics, health sciences, social sciences, or epidemiology. The applicant should be a collaborator and flexible thinker, intensely and demonstrably interested in qualitative and quantitative research, patient/societal preference research, and oncology particularly breast cancer. The applicant should be motivated to participate in an interdisciplinary research program and to learn in situations that are beyond their current capabilities. The ideal candidate has an interest and preferably experience in qualitative (e.g. semi-structured interviews, focus groups) and quantitative research methods (e.g. discrete choice experiments). Knowledge of and experience in preference measurement are a distinct and desirable advantage. The applicant must have excellent communication and writing skills in both Dutch and English.

Conditions of employment

We offer you an internationally oriented and varied job in an enthusiastic team, with excellent working conditions in accordance with the Collective Labour Agreement for Dutch Universities (CAO-NU).

The start date of this position is 01-APR-2025 and you will be based at Erasmus School of Health Policy & Management (ESHPM). This position is for 1 fte. The salary ranges from a minimum of € 2.901 to a maximum of € 3.707 gross per month Scale PhD on a fulltime basis (38 hours), in accordance with the CAO-NU. The contract is entered into for the duration of (contractduur).

Everything else we offer you, you can find below!

Employer

Erasmus University Rotterdam

Erasmus University Rotterdam (EUR) is an internationally oriented university with a strong social orientation in its education and research, as expressed in our mission ‘Creating positive societal impact’. EUR is home to 4.100 academics and professionals and almost 33.000 students from more than 140 countries. Everything we do, we do under the credo The Erasmian Way – Making Minds Matter. We’re global citizens, connecting, entrepreneurial, open-minded, and socially involved. These Erasmian Values function as our internal compass and create EUR’s distinctive and recognizable profile. From these values, with a broad perspective and with an eye for diversity, different backgrounds and opinions, our employees work closely together to solve societal challenges from the dynamic and cosmopolitan city of Rotterdam. Thanks to the high quality and positive societal impact of our research and education, EUR can compete with the top European universities. www.eur.nl.

Faculty / Institute / Central service
Erasmus School of Health Policy & Management (ESHPM) is part of Erasmus University Rotterdam and is responsible for a bachelors and three (international) master programs on health policy, economics and management, serving more than 1,300 students. ESHPM is a multidisciplinary school with research focusing on three main themes: ‘competition and regulation in healthcare’; ‘quality and efficiency in healthcare’; and ‘healthcare management’. The position is offered in the Health Technology Assessment group.

Specifications

  • PhD scholarship
  • max. 40 hours per week
  • €2901—€3707 per month
  • University graduate
  • 4685

Employer

Erasmus University Rotterdam (EUR)

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Location

Burgemeester Oudlaan 50, 3062PA, Rotterdam

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