At Amsterdam UMC, under the leadership of Professor Elga de Vries, our research group is dedicated to understanding the complex interplay between the immune system and neurodegenerative diseases, particularly dementia and multiple sclerosis.

We investigate the roles of neuroinflammation and neurovascular dysfunction in cognitive disorders, aiming to identify biomarkers and therapeutic targets that can lead to innovative treatments. Our collaborative and dynamic environment fosters cutting-edge research that seeks to revolutionize patient care and enhance brain health.

We are seeking a dedicated and organized Research Technician to join our team.

• The ideal candidate will have a strong background in cell biology, particularly in working with human induced pluripotent stem cells (hiPSCs) and CRISPR/Cas9 gene-editing techniques.
• This role requires both independent and collaborative work, where your expertise will directly contribute to innovative research projects.
• Generate and maintain iPSC lines, with a focus on astrocyte and/or endothelial cell differentiation.
• Perform quality control assays on iPSCs, including viability, sterility and pluripotency validation.
• Develop, optimize and implement QC protocols and SOPs for iPSC production.
• Keep meticulous records of cell line data and experimental protocols.
• Utilize CRISPR-Cas technology for gene editing and manipulation.
• Collaborate effectively with team members while also managing individual projects.
• Assist in troubleshooting experiments and optimizing protocols.
• Participate in lab meetings and contribute to research discussions.

• (Bachelor’s or Master’s degree in Cell Biology, Molecular Biology, or a related field.) Completed bachelor's degree in Higher Laboratory Education/Biology and Medical Laboratory Research/comparable, with an affinity for neuroscience.
• Proven experience with iPSC culture and differentiation techniques.
• Familiarity with CRISPR-Cas technology and its applications in research.
• Strong organizational skills and attention to detail.
• Ability to work both independently and as part of a team.
• Excellent communication skills.

Preferred Qualifications:

• Experience in a research laboratory setting.
• Knowledge of astrocyte and endothelial cell biology and related research methods.
• Previous experience in maintaining cell lines and performing genetic modifications.

• A flying start to your career in scientific research.
• Plenty of room for your drive to shape tomorrow's healthcare.
• Working on large-scale and in-house research, with motivated colleagues from all over the world.
• You will be employed by Amsterdam UMC Research BV.
• A contract for 12 months (extension for 2 years is possible, subject to funding).
• Salary scale 7M: € 2.975 to € 4.214 gross based on full-time employment (depending on education and experience) and a year-end bonus of 8.3%. Calculate your net salary here.
• Holiday hours: 186,4 per year for fulltime and a possibility to save additional hours.
• Pension accrual with BeFrank, a modern, comprehensible and fairly priced pension.
• For >7 km each way, 100% reimbursement for public transport travel costs and, for private transport, €0.18 per km up to a maximum of 40 km each way.
• Do you prefer walking or cycling? Take advantage of our good bike scheme. Moreover, you will receive a reimbursement of €0.18 per km.

Watch this video with more information about joining Amsterdam UMC Research BV.

Amsterdam UMC

The Department of Molecular Cell Biology and Immunology (MCBI) at the Amsterdam UMC (VUmc location) carries out research at an internationally competitive level and offers a stimulating and collegial work environment.

The research of the department concentrates on immunological questions in the fields of cancer, neuroimmunology, skin biology, and inflammation. The research focuses on both, fundamental questions aimed at unraveling molecular and cellular mechanisms and translational research focusing on the application of fundamental knowledge to medical questions.

Amsterdam UMC Research BV supports non-profit scientific research. In doing so, we provide researchers with everything they need to excel. Our principal investigators (PIs) and project leaders offer support in the field of project management, finance and human resources. In medical scientific research projects, legal support is also provided.

Watch the video to find out more.

During the publication period, applications will be handled continuously. If the vacancy is filled, it will be closed prematurely.

If you have any questions about this position, please feel free to contact Prof. dr. H.E. de Vries, via he.devries@amsterdamumc.nl or Dr. N.M. de Wit via N.dewit1@amsterdamumc.nl.

For more information about the application process, please contact Tanja Hart, Recruitment advisor, via 06-21603178 or via t.hart@amsterdamumc.nl.

A reference check, screening and hiring test may be part of the procedure. Read here whether that applies to you. If you join us, we ask you for a VOG (Certificate of Good Conduct).

Internal candidates will be given priority over external candidates in case of equal suitability.

Acquisition in response to this vacancy is not appreciated.